For a full publication list, please see here.

M. Nasreen, D. Ellis, J. Hosmer, A.-T. Essilfie, E. Fantino, P. Sly, A.G. McEwan, and U. Kappler, The DmsABC S-oxide reductase is an essential component of a novel, hypochlorite-inducible system of extracellular stress defense in Haemophilus influenzae. Front Microbiol 15 (2024).

U. Kappler, A. Henningham, M. Nasreen, A. Yamamoto, A.H. Buultjens, T.P. Stinear, P. Sly, and E. Fantino, Tolerance to Haemophilus influenzae infection in human epithelial cells: Insights from a primary cell-based model. PLoS Pathog 20 (2024) e1012282.

K. Ganio, M. Nasreen, Z. Yang, E.A. Maunders, Z. Luo, S.I. Hossain, D.H.Y. Ngu, D. Ellis, J. Gu, S.L. Neville, J. Wilksch, A.P. Gunn, J.J. Whittall, B. Kobe, E. Deplazes, U. Kappler, and C.A. McDevitt, Hfe Permease and Haemophilus influenzae Manganese Homeostasis. ACS Infect Dis 10 (2024) 436-452.

M.-D. Phan, H.J. Schirra, N.T.K. Nhu, K.M. Peters, S. Sarkar, L.P. Allsopp, M.E.S. Achard, U. Kappler, and M.A. Schembri, Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant Escherichia coli ST131. mBio 15 (2024) e03388-23.

J. Hosmer, A.G. McEwan, and U. Kappler, Bacterial acetate metabolism and its influence on human epithelia. Emerging Topics in Life Sciences (2023).

U. Kappler, and J.T.H. Wang, Exploring the utility of virtual laboratory training tools. Microbiology Australia 44 (2023) 149-151.

U. Kappler, A. Henningham, M. Nasreen, A.H. Buultjens, T.P. Stinear, P. Sly, and E. Fantino, Tolerance to Haemophilus influenzae infection in human epithelial cells: insights from a primary cell-based model. bioRxiv (2023) 2023.07.11.548529.

J. Hosmer, M. Nasreen, R. Dhouib, A.-T. Essilfie, H.J. Schirra, A. Henningham, E. Fantino, P. Sly, A.G. McEwan, and U. Kappler, Access to highly specialized growth substrates and production of epithelial immunomodulatory metabolites determine survival of Haemophilus influenzae in human airway epithelial cells. PLoS Pathog 18 (2022) e1010209.

M. Nasreen, R.P. Nair, A.G. McEwan, and U. Kappler, The Peptide Methionine Sulfoxide Reductase (MsrAB) of Haemophilus influenzae Repairs Oxidatively Damaged Outer Membrane and Periplasmic Proteins Involved in Nutrient Acquisition and Virulence. Antioxidants 11 (2022) 1557.

M.S.I. Wizrah, S.M.H. Chua, Z. Luo, M.K. Manik, M. Pan, J.M.L. Whyte, A.A.B. Robertson, U. Kappler, B. Kobe, and J.A. Fraser, AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans. J Biol Chem 298 (2022) 102453.

M. Nasreen, A. Fletcher, J. Hosmer, Q. Zhong, A.-T. Essilfie, A.G. McEwan, and U. Kappler, The alternative sigma factor RpoE2 is involved in the stress response to hypochlorite and in vivo survival of Haemophilus influenzae. Front Microbiol 12 (2021) 10.3389/fmicb.2021.637213.

J. Borlinghaus, J. Foerster , U. Kappler, H. Antelmann, U. Noll, M.C.H. Gruhlke, and A.J. Slusarenko, Allicin, the Odor of Freshly Crushed Garlic: A Review of Recent Progress in Understanding Allicin’s Effects on Cells. Molecules 26 (2021) 1505.

S.M.H. Chua, M.S.I. Wizrah, Z. Luo, B.Y.J. Lim, U. Kappler, B. Kobe, and J.A. Fraser, Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets. J Biol Chem 297 (2021) 101091.

R. Dhouib, M. Nasreen, D. Othman, D. Ellis, S. Lee, A.T. Essilfie, P.M. Hansbro, A.G. McEwan, and U. Kappler, The DmsABC sulfoxide reductase supports virulence in non-typeable Haemophilus influenzae. Front Microbiol 12 (2021) 686833.

M.A. Struwe, P. Kalimuthu, Z. Luo, Q. Zhong, D. Ellis, J. Yang, K.C. Khadanand, J.R. Harmer, M.L. Kirk, A.G. McEwan, B. Clement, P.V. Bernhardt, B. Kobe, and U. Kappler, Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes. J Biol Chem 296 (2021) 100672.

U. Kappler, Metals, Microbes, and Minerals: The Biogeochemical Side of Life, Vol. 21 of Metal Ions in Life Sciences - Book Review. Journal of Inorganic Biochemistry 221 (2021) 111488.

U. Kappler, Science meets Parliament 2021. Microbiology Australia 42 (2021) 100-100.

N. López-López, B. Euba, J. Hill, R. Dhouib, L.a. Caballero, J. Leiva, J. Hosmer, S. Cuesta, J. Ramos-Vivas, R. Díez-Martínez, H.J. Schirra, L.M. Blank, U. Kappler, and J. Garmendia, Haemophilus influenzae Glucose Catabolism Leading to Production of the Immunometabolite Acetate Has a Key Contribution to the Host Airway–Pathogen Interplay. ACS Infect. Dis. 6 (2020) 406-421.

Q. Zhong, B. Kobe, and U. Kappler, Molybdenum Enzymes and How They Support Virulence in Pathogenic Bacteria. Front Microbiol 11 (2020).

M. Nasreen, R. Dhouib, J. Hosmer, H.G.S. Wijesinghe, A. Fletcher, M. Mahawar, A.-T. Essilfie, P.J. Blackall, A.G. McEwan, and U. Kappler, Peptide methionine sulfoxide reductase from Haemophilus influenzae is required for protection against HOCl and affects the host response to infection. ACS Infect. Dis. 6 (2020) 1928-1939.